Article
Autogenous regulation of the Bacillus anthracis pag operon.
Journal of bacteriology - 1 Aug 1999
Hoffmaster A R, Koehler T M
Abstract excerpt
Protective antigen (PA) is an important component of the edema and lethal toxins produced by Bacillus anthracis. PA is essential for binding the toxins to the target cell receptor and for facilitating translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. The structural gene for PA, pagA (previously known as pag), is located on the 182-kb virulence...
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