Article
The application of a linear algebra to the analysis of mutation rates.
Journal of theoretical biology - 7 Jul 1999
Jones M E, Thomas S M, Clarke K
Abstract excerpt
Cells and bacteria growing in culture are subject to mutation, and as this mutation is the ultimate substrate for selection and evolution, the factors controlling the mutation rate are of some interest. The mutational event is not observed directly, but is inferred from the phenotype of the original mutant or of its descendants; the rate of mutation is inferred from the number of such mutant phenotypes. Such...
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