Article
Progress of a half century in the study of the Luria-Delbrück distribution.
Mathematical biosciences - 1 Jan 2000
Zheng Q
Abstract excerpt
The Luria-Delbrück mutation model has been mathematically formulated in a number of ways. This review article examines four most important formulations, focusing on important practical issues closely linked with the distribution of the number of mutants. These issues include the probability generating functions, moments (cumulants), computational methods and asymptotics. This review emphasizes basic principles...
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