Article
Entorhinal cortex beta-amyloid load in individuals with mild cognitive impairment.
Experimental neurology - 1 Aug 1999
Mufson E J, Chen E Y, Cochran E J, Beckett L A, Bennett D A, Kordower J H
Abstract excerpt
The deposition of beta-amyloid within the entorhinal cortex (EC) may play a key role in the development of mild cognitive impairment (MCI) in the elderly. To examine the relationship of beta-amyloid deposition to MCI, EC tissue immunostained for this protein was quantitated from a cohort of aged Catholic religious clergy with a clinical diagnosis of MCI and compared to those with no cognitive impairment (NCI) and...
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