Article
Long-term response to interferon alpha is unrelated to "interferon sensitivity determining region" variability in patients with chronic hepatitis C virus-1b infection.
Journal of hepatology - 1 Jun 1999
Squadrito G, Orlando M E, Cacciola I, Rumi M G, Artini M, Picciotto A, Loiacono O, Siciliano R, Levrero M, Raimondo G
Abstract excerpt
BACKGROUND/AIMS: Contradictory data have been reported about the predictive value of the variability in interferon sensitivity determining region (ISDR) of hepatitis C virus (HCV) genotype-1b on response to interferon-alpha (IFN-alpha) therapy. The aim of this study was to examine this issue in a series of patients with long-term response to IFN treatment. METHODS: We retrospectively analyzed 24 patients with...
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