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Article

Transcription factor NF1 mediates repression of the GLUT4 promoter by cyclic-AMP.

Biochemical and biophysical research communications - 14 Jul 1999

Cooke D W, Lane M D

Abstract excerpt

Prolonged treatment of 3T3-L1 adipocytes with 8-Br-cAMP decreases expression of GLUT4, the insulin-responsive glucose transporter. Expression of a promoter-reporter gene construct that contained 785 base pairs of 5'-flanking region of the murine GLUT4 gene was down regulated by 8-Br-cAMP (p < 0.001), whereas expression of constructs that contained 641 or 469 base pairs of 5'-flanking region was not. A reporter...

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Identifiers

PMID: 10403812
DOI: 10.1006/bbrc.1999.0959

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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