Article
A visual screen of a GFP-fusion library identifies a new type of nuclear envelope membrane protein.
The Journal of cell biology - 12 Jul 1999
Rolls M M, Stein P A, Taylor S S, Ha E, McKeon F, Rapoport T A
Abstract excerpt
The nuclear envelope (NE) is a distinct subdomain of the ER, but few membrane components have been described that are specific to it. We performed a visual screen in tissue culture cells to identify proteins targeted to the NE. This approach does not require assumptions about the nature of the association with the NE or the physical separation of NE and ER. We confirmed that screening a library of fusions to the...
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