Article
Purification, Characterization, and Role of Nucleases and Serine Proteases in Streptomyces Differentiation
1 Jul 1999
Abstract excerpt
Two exocellular nucleases with molecular masses of 18 and 34 kDa, which are nutritionally regulated and reach their maximum activity during aerial mycelium formation and sporulation, have been detected in Streptomyces antibioticus. Their function appears to be DNA degradation in the substrate mycelium, and in agreement with this proposed role the two nucleases cooperate efficiently with a periplasmic nuclease...