Article
Immunoglobulin VH gene expression among extranodal marginal zone B-cell lymphomas of the ocular adnexa.
Investigative ophthalmology & visual science - 1 Mar 1999
Coupland S E, Foss H D, Anagnostopoulos I, Hummel M, Stein H
Abstract excerpt
PURPOSE: Most lymphomas of the ocular adnexa are primary extranodal non-Hodgkin's lymphomas of the B-cell type, with the most common lymphoma subtype being the extranodal marginal-zone B-cell lymphoma (EMZL). Analysis of somatic mutations in the variable (V) region of the Ig heavy (H)-chain gene segment suggests that EMZL development in other locations is dependent on antigen stimulation. The purpose of this...
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