Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rho-dependent regulation of cell spreading by the tetraspan membrane protein Gas3/PMP22.

Molecular biology of the cell - 1 Jul 1999

Brancolini C, Marzinotto S, Edomi P, Agostoni E, Fiorentini C, Müller H W, Schneider C

Abstract excerpt

Gas3/PMP22 plays a crucial role in regulating myelin formation and maintenance, and different genetic alterations in gas3/PMP22 are responsible for a set of human peripheral neuropathies. We have previously demonstrated that Gas3/PMP22 could regulate susceptibility to apoptosis in NIH3T3 cells but not in REF 52 cells. In this report we demonstrate that when the apoptotic response triggered by gas3/PMP22 was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Androstadienes
Share to Cell Size
Share to Charcot-Marie-Tooth Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytotoxins

Share to Myelin Proteins

Share to rhoA GTP-Binding Protein

Share to Schwann Cells

Share to Wortmannin

Source

Open in PubMed Open full text

Identifiers

PMID: 10397775
DOI: 10.1091/mbc.10.7.2441
PMCID: PMC25466

Genes

PMP22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rho-dependent regulation of cell spreading by the tetraspan membrane protein Gas3/PMP22.PMID 10397775Read ↗

Apoptotic phenotype induced by overexpression of wild-type gas3/PMP22: its relation to the demyelinating peripheral neuropathy CMT1A.Semantic proximity Read ↗

Alterations in the Arf6-regulated plasma membrane endosomal recycling pathway in cells overexpressing the tetraspan protein Gas3/PMP22Semantic proximity Read ↗

The palmitoylation state of PMP22 modulates epithelial cell morphology and migration.Semantic proximity Read ↗

Upregulation of myelin and lymphocyte protein (MAL) after traumatic spinal cord injury in rats.Semantic proximity Read ↗

Uncoupling of neuroinflammation from axonal degeneration in mice lacking the myelin protein tetraspanin-2.Semantic proximity Read ↗

Peripheral Myelin Protein 22 Preferentially Partitions into Ordered Phase Membrane DomainsSemantic proximity Read ↗

Knockdown of Rab7B, but not of Rab7A, which antagonistically regulates oligodendroglial cell morphological differentiation, recovers tunicamycin-induced defective differentiation in FBD-102b cellsSemantic proximity Read ↗

The RhoG-Binding Domain of ELMO1 Rescues the PTENopathy-like Phenotype in Oligodendroglial FBD-102b Cells.Semantic proximity Read ↗

SNARE mimicry by the CD225 domain of IFITM3 enables regulation of homotypic late endosome fusionSemantic proximity Read ↗

Recessive, but not dominant, mutations in peripheral myelin protein 22 gene show unique patterns of aggregation and intracellular trafficking.Semantic proximity Read ↗

RRP22 Is a Farnesylated, Nucleolar, Ras-Related Protein with Tumor Suppressor PotentialSemantic proximity Read ↗

Non-cell-autonomous function of DR6 in Schwann cell proliferation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.