Article
Mutational analysis of phospholipase A2A: a positional candidate susceptibility gene for bipolar disorder.
Molecular psychiatry - 1 May 1999
Jacobsen N J, Franks E K, Owen M J, Craddock N J
Abstract excerpt
Evidence for the involvement of genetic factors in the pathogenesis of bipolar affective disorder is now well established. However, the mode of inheritance is non-mendelian and this makes the identification of susceptibility loci difficult. A short-cut to localisation of a disease gene for an oligogenic/multifactorial disorder such as bipolar disorder may come from observation of cosegregation with a monogenic...
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