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Article

Mitotic Kinase Expression and Colorectal Cancer Progression

7 Jul 1999

Abstract excerpt

Loss of chromosomal integrity as well as genomic stability is considered to act as a driving force during the processes of tumorigenesis and tumor progression ( 1 - 3 ). Recently, two kinase genes involved in mitosis, the genes for aurora and IPL1-like midbody-associated protein kinase-1 ( 4 , 5 ) [AIM-1, registered in UniGene and also known as aurora1 ( 6 ) and ARK2 ( 7 )] and for serine/threonine kinase-6...

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PMID: 10393726
DOI: 10.1093/jnci/91.13.1160

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