Article
Assembly of Saccharomyces cerevisiae 60S ribosomal subunits: role of factors required for 27S pre-rRNA processing.
The EMBO journal - 16 Sept 2011
Sahasranaman Aarti, Dembowski Jill, Strahler John, Andrews Philip, Maddock Janine, Woolford John L
Abstract excerpt
The precise functions of most of the ∼200 assembly factors and 79 ribosomal proteins required to construct yeast ribosomes in vivo remain largely unexplored. To better understand the roles of these proteins and the mechanisms driving ribosome biogenesis, we examined in detail one step in 60S ribosomal subunit assembly-processing of 27SA(3) pre-rRNA. Six of seven assembly factors required for this step (A(3)...
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