Article
A temperature sensitive mutant of Saccharomyces cerevisiae defective in pre-rRNA processing.
Nucleic acids research - 25 Sept 1991
Shuai K, Warner J R
Abstract excerpt
A recessive temperature sensitive mutant has been isolated that is defective in ribosomal RNA processing. By Northern analysis, this mutant was found to accumulate three novel rRNA species: 23S', 18S' and 7S', each of which contains sequences from the spacer region between 25S and 18S rRNA. 35S pre-rRNA accumulates, while the level of the 20S and 27S rRNA processing intermediates is depressed. Pulse-chase...
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