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Article

A temperature sensitive mutant of Saccharomyces cerevisiae defective in pre-rRNA processing.

Nucleic acids research - 25 Sept 1991

Shuai K, Warner J R

Abstract excerpt

A recessive temperature sensitive mutant has been isolated that is defective in ribosomal RNA processing. By Northern analysis, this mutant was found to accumulate three novel rRNA species: 23S', 18S' and 7S', each of which contains sequences from the spacer region between 25S and 18S rRNA. 35S pre-rRNA accumulates, while the level of the 20S and 27S rRNA processing intermediates is depressed. Pulse-chase...

Topics

Blotting, Northern
Mutation
Oligonucleotide Probes
RNA Precursors
RNA, Ribosomal
RNA, Ribosomal, 18S
RNA, Ribosomal, 23S
Ribosomes
Saccharomyces cerevisiae
Temperature

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Identifiers

PMID: 1923772
DOI: 10.1093/nar/19.18.5059
PMCID: PMC328810

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1923772-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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