Article
Contribution of HLA class II genes to susceptibility in achalasia.
Tissue antigens - 1 Oct 1998
De la Concha E G, Fernandez-Arquero M, Mendoza J L, Conejero L, Figueredo M A, Perez de la Serna J, Diaz-Rubio M, Ruiz de Leon A
Abstract excerpt
Achalasia is a motor disorder of the esophagus resulting in functional obstruction. The cause of the lesion is unknown although genetic and immunologic factors have been suggested. An association with serological HLA epitopes has been previously reported. In this study, we have further examined this HLA class II association with susceptibility to achalasia by DNA based methods. Achalasia patients (n=40) and...
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