Article
The expression and function of cadherin-mediated cell-to-cell adhesion in human embryonal carcinoma cells.
Mechanisms of development - 1 May 1999
Giesberts A N, Duran C, Morton I N, Pigott C, White S J, Andrews P W
Abstract excerpt
Human embryonal carcinoma (EC) cells typically require high cell densities to maintain their characteristic phenotype; they are generally subject to differentiation when cultured at low cell densities, marked by changes in morphology and expression of the surface antigen, SSEA-1. To test whether cadherin mediated cell-to-cell adhesion may be responsible for maintaining an EC phenotype we ascertained that human EC...
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