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Article

The maternal NF-kappaB/dorsal gradient of Tribolium castaneum: dynamics of early dorsoventral patterning in a short-germ beetle.

Development (Cambridge, England) - 1 Dec 2000

Chen G, Handel K, Roth S

Abstract excerpt

In the long-germ insect Drosophila melanogaster dorsoventral polarity is induced by localized Toll-receptor activation which leads to the formation of a nuclear gradient of the rel/ NF-kappaB protein Dorsal. Peak levels of nuclear Dorsal are found in a ventral stripe spanning the entire length of the blastoderm embryo allowing all segments and their dorsoventral subdivisions to be synchronously specified before...

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Source

Identifiers

PMID: 11060240
DOI: 10.1242/dev.127.23.5145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The maternal NF-kappaB/dorsal gradient of Tribolium castaneum: dynamics of early dorsoventral patterning in a short-germ beetle.PMID 11060240Read ↗

Genome-wide identification of Tribolium dorsoventral patterning genes.Semantic proximity Read ↗

Toll homologue expression in the beetle tribolium suggests a different mode of dorsoventral patterning than in drosophila embryos.Semantic proximity Read ↗

FGF signalling controls anterior extraembryonic and embryonic fate in the beetle Tribolium.Semantic proximity Read ↗

Quantitative imaging of the Dorsal nuclear gradient reveals limitations to threshold-dependent patterning in Drosophila.Semantic proximity Read ↗

Conservation of enhancer location in divergent insects.Semantic proximity Read ↗

A deficiency of the homeotic complex of the beetle Tribolium.Semantic proximity Read ↗

Apparent role of Tribolium orthodenticle in anteroposterior blastoderm patterning largely reflects novel functions in dorsoventral axis formation and cell survival.Semantic proximity Read ↗

Candidate gene screen in the red flour beetle Tribolium reveals six3 as ancient regulator of anterior median head and central complex development.Semantic proximity Read ↗

Delimiting the conserved features of hunchback function for the trunk organization of insects.Semantic proximity Read ↗

The Tribolium homeotic gene Abdominal is homologous to abdominal-A of the Drosophila bithorax complex.Semantic proximity Read ↗

Structure and function of the homeotic gene complex (HOM-C) in the beetle, Tribolium castaneum.Semantic proximity Read ↗

RTK signaling modulates the Dorsal gradient.Semantic proximity Read ↗

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