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Suspected hereditary nonpolyposis colorectal cancer

1 Jun 1999

Abstract excerpt

PURPOSE: The aim of this study was to determine the frequency of mutations in the mismatch repair genes in families suspected of having hereditary nonpolyposis colorectal cancer. METHODS: We devised two criteria for families suspected of having hereditary nonpolyposis colorectal cancer (Criteria I and II). Criteria I consist of at least two first-degree relatives affected with colorectal cancer with at least one...

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PMID: 10378593
DOI: 10.1007/bf02236922

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