Article
The role of hereditary nonpolyposis colorectal cancer in the management of familial ovarian cancer.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Oct 2006
Farrell Carolyn, Lyman Mollie, Freitag Katherine, Fahey Cathy, Piver M Steven, Rodabaugh Kerry J
Abstract excerpt
PURPOSE: Familial ovarian cancer is most often associated with hereditary breast and ovarian cancer, implicating mutations in the BRCA1 and BRCA2 genes. Hereditary nonpolyposis colorectal cancer, another common syndrome, is also associated with ovarian cancer and is caused by DNA mismatch repair...
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