Article
Paraoxonase 1 mutations in a Turkish population.
Toxicology and applied pharmacology - 15 Jun 1999
Aynacioglu A S, Cascorbi I, Mrozikiewicz P M, Nacak M, Tapanyigit E E, Roots I
Abstract excerpt
Human serum paraoxonase 1 (PON1) catalyzes the hydrolysis of certain organophosphate pesticides and nerve gases and so may alter significantly an individual's susceptibility to the toxicity of these chemicals. Moreover, PON1 hydrolyzes lipid peroxides complexed to low density lipoproteins (LDL) and therefore it was suggested that PON1 may be one of the genes that is involved in the pathogenesis of cardiovascular...
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