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Article

Progressive cis-inhibition of telomerase upon telomere elongation.

The EMBO journal - 15 Jun 1999

Marcand S, Brevet V, Gilson E

Abstract excerpt

In yeast, the constant length of telomeric DNA results from a negative regulation of telomerase by the telomere itself. Here we follow the return to equilibrium of an abnormally shortened telomere. We observe that telomere elongation is restricted to a few base pairs per generation and that its rate decreases progressively with increasing telomere length. In contrast, in the absence of telomerase or in the...

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Identifiers

PMID: 10369690
DOI: 10.1093/emboj/18.12.3509
PMCID: PMC1171430

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Progressive cis-inhibition of telomerase upon telomere elongation.PMID 10369690Read ↗

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