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Article

Association of polymorphism in glutathione S-transferase loci with susceptibility and outcome in rheumatoid arthritis: comparison with the shared epitope.

Annals of the rheumatic diseases - 1 Mar 1999

Mattey D L, Hassell A B, Plant M, Dawes P T, Ollier W R, Jones P W, Fryer A A, Alldersea J E, Strange R C

Abstract excerpt

OBJECTIVE: To determine whether glutathione S-transferase GSTM1, GSTM3, GSTT1, and GSTP1 genotypes influence susceptibility or outcome in rheumatoid arthritis (RA). METHODS: 277 RA patients were compared with 577 controls to examine any associations between GST genotypes and susceptibility to RA. The effect of genotypes on outcome (Larsen and functional scores) and time integrated acute phase responses...

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Topics

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Share to Aged, 80 and over
Share to Arthritis, Rheumatoid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chi-Square Distribution

Share to Glutathione Transferase

Share to HLA-DR Antigens

Share to HLA-DRB1 Chains

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Source

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Identifiers

PMID: 10364914
DOI: 10.1136/ard.58.3.164
PMCID: PMC1752853

Genes

GSTM1
GSTM3
GSTP1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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