Article
Glutathione S-transferase gene polymorphisms in Japanese patients with rheumatoid arthritis.
Clinical and experimental rheumatology - 1 Jan 2000
Morinobu S, Morinobu A, Kanagawa S, Hayashi N, Nishimura K, Kumagai S
Abstract excerpt
OBJECTIVE: To investigate the role of polymorphisms of the glutathione S-transferase M1 (GSTM1), GSTT1, and GSTP1 genes in determining susceptibility to rheumatoid arthritis (RA) and association with the clinical features. METHODS: Polymorphisms of the GSTM1, GSTT1, and GSTP1 genes in 108 Japanese patients with RA and in 143 healthy controls were analyzed by polymerase chain reaction (PCR) or PCR-restriction...
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