Article
Independent association of rheumatoid factor and the HLA-DRB1 shared epitope with radiographic outcome in rheumatoid arthritis.
Arthritis and rheumatism - 1 Jul 2001
Mattey D L, Hassell A B, Dawes P T, Cheung N T, Poulton K V, Thomson W, Hajeer A H, Ollier W E
Abstract excerpt
OBJECTIVE: Findings of a recent study suggested that HLA-DRB1 alleles encoding the rheumatoid arthritis (RA) "shared epitope" (SE) were not predictive of erosive damage at 2 years in patients with early inflammatory arthritis who were rheumatoid factor (RF) positive, but were predictive in those who were RF negative. The present study was undertaken to determine whether RF status was also important in the...
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