Article
Linkage to nodal osteoarthritis: quantitative and qualitative analyses of data from a whole-genome screen identify trait-dependent susceptibility loci.
Annals of the rheumatic diseases - 1 Sept 2006
Greig C, Spreckley K, Aspinwall R, Gillaspy E, Grant M, Ollier W, John S, Doherty M, Wallis G
Abstract excerpt
OBJECTIVE: To identify susceptibility loci for nodal osteoarthritis. METHODS: A genome screen at an average marker spacing of 9.29 cM was carried out on 558 people from 202 families, of whom 491 had nodal osteoarthritis. All genotyped people were graded for the incidence and severity of distal interphalangeal (DIP) nodes, and radiographs from 354 people were graded for joint-space narrowing (JSN) and osteophytes...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
