Article
Genomewide linkage study in 1,176 affected sister pair families identifies a significant susceptibility locus for endometriosis on chromosome 10q26.
American journal of human genetics - 1 Sept 2005
Treloar Susan A, Wicks Jacqueline, Nyholt Dale R, Montgomery Grant W, Bahlo Melanie, Smith Vicki, Dawson Gary, Mackay Ian J, Weeks Daniel E, Bennett Simon T, Carey Alisoun, Ewen-White Kelly R, Duffy David L, O'connor Daniel T, Barlow David H, Martin Nicholas G, Kennedy Stephen H
Abstract excerpt
Endometriosis is a common gynecological disease that affects up to 10% of women in their reproductive years. It causes pelvic pain, severe dysmenorrhea, and subfertility. The disease is defined as the presence of tissue resembling endometrium in sites outside the uterus. Its cause remains uncertain despite >50 years of hypothesis-driven research, and thus the therapeutic options are limited. Disease...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.