Article
Neuropeptide Y Y1 receptor polymorphism as a prognostic predictor in Japanese patients with IgA nephropathy.
Clinical nephrology - 1 May 1999
Ito H, Morita T, Suehiro T, Tahara K, Ikeda Y, Nakauchi Y, Makino S, Nishiya K, Hashimoto K
Abstract excerpt
BACKGROUND: Neuropeptide Y exhibits a vasoconstricting action and regulates systemic blood pressure as well as noradrenalin. There are 5 types of NPY receptors, Y1 - Y5, which were introduced by pharmacological differences. Recently, a single point mutation in the first intron of the NPY Y1 receptor (NPYY1R) was reported. SUBJECTS AND METHODS: In this study, we investigated the relationship between NPYY1R gene...
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