Article
Linkage and association study of neurotrophins and their receptors as novel susceptibility genes for childhood IgA nephropathy.
Pediatric research - 1 Apr 2011
Hahn Won-Ho, Suh Jin-Soon, Cho Byoung-Soo
Abstract excerpt
Neurotrophins (NTs) and their receptors (NTRs) are known to be important for pathogenesis of various inflammatory diseases that occur in not only neuronal but also nonneuronal tissues, including kidney. Here, we investigated association between childhood IgA nephropathy (IgAN) and single nucleotide polymorphisms (SNPs) of genes encoding NTs [nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF)]...
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