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Article

Potentiation of the malignant phenotype of the undifferentiated ARO thyroid cell line by insertion of the bcl-2 gene.

International journal of cancer - 11 Jun 1999

Basolo F, Fiore L, Fusco A, Giannini R, Albini A, Merlo G R, Fontanini G, Conaldi P G, Toniolo A

Abstract excerpt

We have reported that bcl-2 is expressed in normal human thyroid epithelium and that its expression is down-regulated in undifferentiated thyroid tumors. Production of IL-6 was concomitantly down-regulated in these forms. Based on these observations, we analyzed whether insertion of bcl-2 would r...

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Source

Identifiers

PMID: 10362145
DOI: 10.1002/(sici)1097-0215(19990611)81:6<956::aid-ijc19>3.0.co;2-n

Genes

PIGF
TPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10362145-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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