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Article

Sequencing of two HLA-A blank alleles: implications in unrelated bone marrow donor matching.

Transplantation - 27 May 1999

Zanone-Ramseier R, Gratwohl A, Gmür J, Roosnek E, Tiercy J M

Abstract excerpt

BACKGROUND: DNA-based methods can type for HLA antigens with no or very low cell surface expression. The role of such serological blank antigens in bone marrow donor selection is unknown. METHODS: HLA-A serological blank antigens detected in two leukemic patients were cloned and sequenced from genomic DNA. mRNA expression and exon 3 splicing were determined by reverse transcriptase-polymerase chain reaction...

Topics

Alleles
Base Sequence
Bone Marrow Transplantation
HLA-A Antigens
Haplotypes
Histocompatibility Testing
Humans
Leukemia
RNA, Messenger
Reverse Transcriptase Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10360587
DOI: 10.1097/00007890-199905270-00008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-10360587-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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