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Immunogenetics of HLA null alleles: implications for blood stem cell transplantation

16 Nov 2004

Abstract excerpt

The transplantation of haematopoietic stem cells is a potentially curative therapy for a variety of haematological and non-haematological diseases. Matching of donor and recipient for human leucocyte antigens (HLA) is pivotal for the success of blood stem cell transplantation. HLA null alleles are characterized by the lack of a serologically detectable product. Because serological HLA diagnostics are increasingly...

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PMID: 15546342
DOI: 10.1111/j.1399-0039.2004.00322.x

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