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Article

Mutations in Human ARF Exon 2 Disrupt Its Nucleolar Localization and Impair Its Ability to Block Nuclear Export of MDM2 and p53

1 May 1999

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 10360174
DOI: 10.1016/s1097-2765(00)80351-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Mutations in Human ARF Exon 2 Disrupt Its Nucleolar Localization and Impair Its Ability to Block Nuclear Export of MDM2 and p53PMID 10360174Read ↗

Human ARF binds E2F1 and inhibits its transcriptional activitySemantic proximity Read ↗

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A conserved domain in exon 2 coding for the human and murine ARF tumor suppressor protein is required for autophagy induction.Semantic proximity Read ↗

Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.Semantic proximity Read ↗

MDM2-ARF complex regulates p53 sumoylation.Semantic proximity Read ↗

Nucleotide binding by the Mdm2 RING domain facilitates Arf-independent Mdm2 nucleolar localization.Semantic proximity Read ↗

A Novel Nuclear Interactor of ARF and MDM2 (NIAM) That Maintains Chromosomal StabilitySemantic proximity Read ↗

Delocalization and destabilization of the Arf tumor suppressor by the leukemia-associated NPM mutant.Semantic proximity Read ↗

p14ARF nuclear overexpression in aggressive B-cell lymphomas is a sensor of malfunction of the common tumor suppressor pathwaysSemantic proximity Read ↗

Non-Canonical Functions of the ARF Tumor Suppressor in Development and TumorigenesisSemantic proximity Read ↗

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