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Article

H,K-ATPase alpha subunit C-terminal membrane topology: epitope tags in the insect cell expression system.

The Biochemical journal - 15 Jun 1999

Smolka A J, Larsen K A, Schweinfest C W, Hammond C E

Abstract excerpt

The H,K-ATPase responsible for gastric acidification is a heterodimeric (alpha and beta subunit) P-type ATPase, an integral protein of parietal cell apical membranes, which promotes the electroneutral exchange of K+ for protons, is stimulated by K+ and is inhibited by 2-methyl-8-(phenylmethoxy)imidazo[1, 2-alpha]pyridine-3-acetonitrile (SCH 28080). Hydropathy analysis of the catalytic alpha subunit has been...

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PMID: 10359643
PMCID: PMC1220290

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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