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Article

Recombinant production of the amino terminal cytoplasmic region of dengue virus non-structural protein 4A for structural studies.

PloS one - 1 Jan 2014

Hung Yu-Fu, Valdau Olga, Schünke Sven, Stern Omer, Koenig Bernd W, Willbold Dieter, Hoffmann Silke

Abstract excerpt

BACKGROUND: Dengue virus (DENV) is a mosquito-transmitted positive single strand RNA virus belonging to the Flaviviridae family. DENV causes dengue fever, currently the world's fastest-spreading tropical disease. Severe forms of the disease like dengue hemorrhagic fever and dengue shock syndrome are life-threatening. There is no specific treatment and no anti-DENV vaccines. Our recent data suggests that the amino...

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Identifiers

PMID: 24466115
DOI: 10.1371/journal.pone.0086482
PMCID: PMC3900556

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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