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Article

Definition of membrane topology and identification of residues important for transport in subunit a of the vacuolar ATPase.

The Journal of biological chemistry - 7 Oct 2011

Toei Masashi, Toei Satoko, Forgac Michael

Abstract excerpt

Subunit a of the vacuolar H(+)-ATPases plays an important role in proton transport. This membrane-integral 100-kDa subunit is thought to form or contribute to proton-conducting hemichannels that allow protons to gain access to and leave buried carboxyl groups on the proteolipid subunits (c, c', and c″) during proton translocation. We previously demonstrated that subunit a contains a large N-terminal cytoplasmic...

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Identifiers

PMID: 21832060
DOI: 10.1074/jbc.M111.273409
PMCID: PMC3186431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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