Article
C-CAM1 expression: differential effects on morphology, differentiation state and suppression of human PC-3 prostate carcinoma cells.
Oncogene - 27 May 1999
Comegys M M, Carreiro M P, Brown J F, Mazzacua A, Flanagan D L, Makarovskiy A, Lin S H, Hixson D C
Abstract excerpt
Studies in rat prostate and liver have suggested that C-CAM1 is involved in the formation and maintenance of histotypic associations in tissues and possibly tumors. Most recently, C-CAM1 has been shown to suppress tumorigenicity of prostate and colon carcinoma cells. However, the mechanisms whereby C-CAM1 suppresses growth and the relationship of this activity to its proposed role in histotypic interactions...
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