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Article

p300 Modulates Nuclear Morphology in Prostate Cancer

1 Feb 2005

Abstract excerpt

Alterations in nuclear structure distinguish cancer cells from noncancer cells. These nuclear alterations can be translated into quantifiable features by digital image analysis in a process known as quantitative nuclear morphometry. Recently, quantitative nuclear morphometry has been shown to predict metastasis and biochemical recurrence of prostate cancer. However, little is known about the cellular mechanisms...

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PMID: 15705864
DOI: 10.1158/0008-5472.708.65.3

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