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Notch Signaling in B Cell Immune Responses

5 Feb 2021

Abstract excerpt

The Notch signaling pathway is highly evolutionarily conserved, dictating cell fate decisions and influencing the survival and growth of progenitor cells that give rise to the cells of the immune system. The roles of Notch signaling in hematopoietic stem cell maintenance and in specification of T lineage cells have been well-described. Notch signaling also plays important roles in B cells. In particular, it is...

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PMID: 33613531
DOI: 10.3389/fimmu.2020.609324

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