Article
Constrained cell recognition peptides engineered into streptavidin.
Biotechnology progress - 1 Jan 2000
McDevitt T C, Nelson K E, Stayton P S
Abstract excerpt
Streptavidin is widely used as an adaptor molecule in diagnostics, separations, and laboratory assay applications. We have here engineered cell adhesive peptides into the three-dimensional scaffolding of streptavidin to convert streptavidin into a functional protein. The mutations did not alter refolding or tetramer assembly and the slow biotin dissociation rate of wild-type streptavidin was retained. The peptide...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
