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Article

Comparison of features of human lung cancer cell lines and their corresponding tumors.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 May 1999

Wistuba I I, Bryant D, Behrens C, Milchgrub S, Virmani A K, Ashfaq R, Minna J D, Gazdar A F

Abstract excerpt

Although human lung tumor-derived cell lines play an important role in the investigation of lung cancer biology and genetics, there is no comprehensive study comparing the genotypic and phenotypic properties of lung cancer cell lines with those of the individual tumors from which they were derived. We compared a variety of properties of 12 human non-small cell lung carcinoma (NSCLC) cell lines (cultured for a...

Topics

Adult
Aged
Alleles
Aneuploidy
Carcinoma, Non-Small-Cell Lung
Cell Culture Techniques
DNA Mutational Analysis
DNA, Neoplasm
Female
Genes, p53
Genes, ras

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Loss of Heterozygosity

Lung Neoplasms

Male

Microsatellite Repeats

Middle Aged

Neoplasm Proteins

Source

Identifiers

PMID: 10353731

Provenance

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