Article
Mutation of the 9q34 gene TSC1 in sporadic bladder cancer.
Oncogene - 22 Apr 1999
Hornigold N, Devlin J, Davies A M, Aveyard J S, Habuchi T, Knowles M A
Abstract excerpt
Deletions involving chromosome 9 occur in more than 50% of human bladder cancers of all grades and stages. Most involve loss of the whole chromosome or of an entire chromosome arm but some small deletions are found which can be used to define critical regions which may contain tumour suppressor genes. We have localized such a critical region of deletion at 9q34 between the markers D9S149 and D9S66, an interval...
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