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Article

Mutation spectrum of the 9q34 tuberous sclerosis gene TSC1 in transitional cell carcinoma of the bladder.

Cancer research - 15 Nov 2003

Knowles Margaret A, Habuchi Tomonori, Kennedy Wendy, Cuthbert-Heavens Darren

Abstract excerpt

Deletions of the long arm of chromosome 9 are the most common genetic alteration in transitional cell carcinoma (TCC) of the bladder. Several regions of deletion on 9q have been mapped by loss of heterozygosity (LOH) analysis, one of which encompasses one of the two loci for tuberous sclerosis, TSC1, at 9q34. Tuberous sclerosis complex (TSC) is an autosomal dominant condition in which affected individuals develop...

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Topics

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Share to Carcinoma, Transitional Cell
Share to Chromosomes, Human, Pair 9

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Conserved Sequence

Share to Genes, Tumor Suppressor

Share to Polymorphism, Single-Stranded Conformational

Share to Tuberous Sclerosis Complex 1 Protein

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Share to Urinary Bladder Neoplasms

Source

Identifiers

PMID: 14633685

Genes

TSC1

Provenance

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