Article
Screening system for xenosiderophores as potential drug delivery agents in mycobacteria.
Antimicrobial agents and chemotherapy - 1 May 2001
Schumann G, Möllmann U
Abstract excerpt
In order to establish a screening system for xenosiderophores which can be utilized by mycobacteria, we generated a set of mutants of Mycobacterium smegmatis that are blocked in different steps of the well-known iron acquisition system. One mutant with a block in mycobactin biosynthesis was generated from strain mc(2)155 by chemical mutagenesis. The exochelin biosynthesis gene fxbA and the ferric exochelin uptake...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
