Article
The DtxR protein acting as dual transcriptional regulator directs a global regulatory network involved in iron metabolism of Corynebacterium glutamicum.
BMC genomics - 9 Feb 2006
Brune Iris, Werner Hendrikje, Hüser Andrea T, Kalinowski Jörn, Pühler Alfred, Tauch Andreas
Abstract excerpt
BACKGROUND: The knowledge about complete bacterial genome sequences opens the way to reconstruct the qualitative topology and global connectivity of transcriptional regulatory networks. Since iron is essential for a variety of cellular processes but also poses problems in biological systems due to its high toxicity, bacteria have evolved complex transcriptional regulatory networks to achieve an effective iron...
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