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Article

Floor plate and netrin-1 are involved in the migration and survival of inferior olivary neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Jun 1999

Bloch-Gallego E, Ezan F, Tessier-Lavigne M, Sotelo C

Abstract excerpt

During their circumferential migration, the nuclei of inferior olivary neurons translocate within their axons until they reach the floor plate where they stop, although their axons have already crossed the midline to project to the contralateral cerebellum. Signals released by the floor plate, including netrin-1, have been implicated in promoting axonal growth and chemoattraction during axonal pathfinding in...

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Source

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Identifiers

PMID: 10341242
PMCID: PMC6782586

Genes

DCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Floor plate and netrin-1 are involved in the migration and survival of inferior olivary neurons.PMID 10341242Read ↗

Differential roles of Netrin-1 and its receptor DCC in inferior olivary neuron migration.Semantic proximity Read ↗

Motor neuron cell bodies are actively positioned by Slit/Robo repulsion and Netrin/DCC attraction.Semantic proximity Read ↗

Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system.Semantic proximity Read ↗

Netrin-1 Confines Rhombic Lip-Derived Neurons to the CNS.Semantic proximity Read ↗

Axon tracts correlate with netrin-1a expression in the zebrafish embryo.Semantic proximity Read ↗

Netrin-1 Is a Chemorepellent for Oligodendrocyte Precursor Cells in the Embryonic Spinal CordSemantic proximity Read ↗

The slit receptor Rig-1/Robo3 controls midline crossing by hindbrain precerebellar neurons and axons.Semantic proximity Read ↗

Netrin-1 and DCC mediate axon guidance locally at the optic disc: loss of function leads to optic nerve hypoplasia.Semantic proximity Read ↗

Motor axon guidance of the mammalian trochlear and phrenic nerves: dependence on the netrin receptor Unc5c and modifier loci.Semantic proximity Read ↗

Netrin 1 is required for semicircular canal formation in the mouse inner ear.Semantic proximity Read ↗

Netrin 1 regulates ventral tangential migration of guidepost neurons in the lateral olfactory tract.Semantic proximity Read ↗

Netrin 1-mediated chemoattraction regulates the migratory pathway of LHRH neurons.Semantic proximity Read ↗

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