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Article

Motor neuron cell bodies are actively positioned by Slit/Robo repulsion and Netrin/DCC attraction.

Developmental biology - 1 Mar 2015

Kim Minkyung, Fontelonga Tatiana, Roesener Andrew P, Lee Haeram, Gurung Suman, Mendonca Philipe R F, Mastick Grant S

Abstract excerpt

Motor neurons differentiate from a ventral column of progenitors and settle in static clusters, the motor nuclei, next to the floor plate. Within these cell clusters, motor neurons receive afferent input and project their axons out to muscle targets. The molecular mechanisms that position motor neurons in the neural tube remain poorly understood. The floor plate produces several types of guidance cues with...

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Source

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Identifiers

PMID: 25530182
DOI: 10.1016/j.ydbio.2014.12.014
PMCID: PMC4339514

Genes

DCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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