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Article

Investigation of terbinafine as a CYP2D6 inhibitor in vivo.

Clinical pharmacology and therapeutics - 1 May 1999

Abdel-Rahman S M, Gotschall R R, Kauffman R E, Leeder J S, Kearns G L

Abstract excerpt

BACKGROUND: Terbinafine is an orally active antifungal used in the treatment of dermatophytoses. To date, studies evaluating the effect of terbinafine on the cytochromes P450 have failed to show any significant interactions. This prospective open-label study was designed to confirm our previous finding that terbinafine may inhibit CYP2D6. METHODS: Nine healthy volunteers were enrolled in this study-6...

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Source

Identifiers

PMID: 10340911
DOI: 10.1016/S0009-9236(99)70065-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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