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Article

Behavioral effects of tryptophan depletion in seasonal affective disorder associated with the serotonin transporter gene?

Psychiatry research - 22 Mar 1999

Lenzinger E, Neumeister A, Praschak-Rieder N, Fuchs K, Gerhard E, Willeit M, Sieghart W, Kasper S F, Hornik K, Aschauer H N

Abstract excerpt

There is some evidence that the neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) may be involved in the pathogenesis of seasonal affective disorder (SAD). Short-term tryptophan (TRP) depletion was carried out in 18 drug-free remitted patients who met DSM-IV criteria for SAD. Behavioral effe...

Topics

Adult
Affect
Aged
Carrier Proteins
Circadian Rhythm
DNA
Fatigue
Female
Genotype
Heterozygote
Homozygote
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Membrane Glycoproteins

Membrane Transport Proteins

Middle Aged

Nerve Tissue Proteins

Polymerase Chain Reaction

Source

Identifiers

PMID: 10333377
DOI: 10.1016/s0165-1781(99)00009-8

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-10333377-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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Behavioral effects of tryptophan depletion in seasonal affective disorder associated with the serotonin transporter gene?PMID 10333377Read ↗

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