Article
Association between seasonal affective disorder and the 5-HT2A promoter polymorphism, -1438G/A.
Molecular psychiatry - 1 Jan 1999
Enoch M A, Goldman D, Barnett R, Sher L, Mazzanti C M, Rosenthal N E
Abstract excerpt
Genes involved in serotonin metabolism are good candidates for the pathogenesis of seasonal affective disorder (SAD). A functional variant in the serotonin transporter promoter, 5-HTTLPR, has recently been shown to be associated with SAD and seasonality. The purpose of this study was to determine whether -1438G/A, a polymorphism in the 5-HT2A promoter, is associated with SAD and seasonality, and whether it has...
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