Article
Molecular, biochemical, and electrophysiological characterization of Drosophila norpA mutants.
The Journal of biological chemistry - 1 Mar 1996
Pearn M T, Randall L L, Shortridge R D, Burg M G, Pak W L
Abstract excerpt
Inositol phosphate signaling has been implicated in a wide variety of eukaryotic cellular processes. In Drosophila, the phototransduction cascade is mediated by a phosphoinositide-specific phospholipase C (PLC) encoded by the norpA gene. We have characterized eight norpA mutants by electroretinog...
Topics
- Alleles
- Animals
- Drosophila Proteins
- Drosophila melanogaster
- Electroretinography
- Ethyl Methanesulfonate
- Genes, Insect
- Kinetics
- Light
- Mutagenesis
- Phosphatidylinositol Diacylglycerol-Lyase
- Phospholipase C beta
- Phosphoric Diester Hydrolases
- Photoreceptor Cells, Invertebrate
- Polymerase Chain Reaction
- Retina
- Sequence Deletion
- Signal Transduction