Article
Molecular, biochemical, and electrophysiological characterization of Drosophila norpA mutants.
The Journal of biological chemistry - 1 Mar 1996
Pearn M T, Randall L L, Shortridge R D, Burg M G, Pak W L
Abstract excerpt
Inositol phosphate signaling has been implicated in a wide variety of eukaryotic cellular processes. In Drosophila, the phototransduction cascade is mediated by a phosphoinositide-specific phospholipase C (PLC) encoded by the norpA gene. We have characterized eight norpA mutants by electroretinogram (ERG), Western, molecular, and in vitro PLC activity analyses. ERG responses of the mutants show allele-dependent...
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